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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The NOEC of quinic acid is >=  5000 mg/L for Daphnia magna during the test period of 48 h. Accompanying TOC-analysis resulted in mean measured concentrations of 133.6, 572.4 and 2211.0 mg/L in the lowest, middle and highest test concentrations. This corresponds to recovery rates of 97.8, 104.7 and 101.1%, indicating that the test item was stable during the test period of 48 h.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
5 000 mg/L

Additional information

Quinic acid was tested in a static Daphnia magna, Acute Immobilisation Test according to the OECD Guideline 202 for 48 h. Five nominal concentrations between 312.5 and 5000 mg/L were used. Daphnids did not show any adverse effects (including abnormal behaviour) in the controls and test concentrations. The NOEC of quinic acid is >= 5000 mg/L.

Further, in the study, published by Henschel, 1997 the EC50 of the read across substance salicylic acid for Daphnia magna was determined in fresh water for 48 h according to OECD Guideline. The EC50 of salicylic acid is 118 mg/l. In the publication of Sanderson 2009, the LC50 of the read across substance shikimic acid for Daphnia magna is given. The LC50 of shikimic acid is 116 mg/L.