Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 300-644-5
CAS number: 93951-21-4
Reactive Blue 250 has a very high water
solubility. Screening tests for biodegradation of the structural
analogue Reactive Black 5 in water showed that the test item is not
readily biodegradable. However, it is rapidly hydrolysed with a
half-life of 1 to 2 days at pH 7. When Reactive Black 5 was applied to a
sediment/water test system at a final concentration of 1 mg/kg in the
test system, the test item was rapidly degraded to Reactive Black 5
bis-vinyl and further to Reactive Black 5-OH. The DT50 of Reactive Black
5-ester was 2 days. After 3 to 6 days, only 10% of the applied Reactive
Black 5 could be found. All metabolites decreased at the end of the test
period to levels around the lower level of quantification. Consequently,
an accumulation of metabolites could be excluded. The majority of the
metabolites of Reactive Black 5 was deposited in form of non-extractable
residues in sediment during test phase. After about 1 month,
mineralization of the metabolites started.
A bioaccumulation study in the carp revealed
bioconcentration factors < 11 for 0.2 mg/L and < 1.1 for 2 mg/L. Hence,
Reactive Black 5 does not bioaccumulate in the aquatic compartment.
Based on data from kinetic and metabolism studies in rats (oral and
intravenous administration), Reactive Black 5 as well as its structural
analogue Reactive Blue 250 does not have any bioaccumulation potential
in animals. Due to the very low toxicity, rapid degradation and lack of
bioaccumulative properties, secondary poisoning can be excluded.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again