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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to microorganisms, other
Remarks:
Microtox test
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
according to guideline
Guideline:
other: Microtox assay
Principles of method if other than guideline:
Microtox assay
GLP compliance:
not specified
Test organisms (species):
Vibrio fisheri
Test type:
static
Water media type:
brackish water
Total exposure duration:
15 min
Duration:
15 min
Dose descriptor:
other: IC20
Effect conc.:
> 0.3 - < 0.7 µmol/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: 95% CL
Duration:
15 min
Dose descriptor:
IC50
Effect conc.:
> 2.8 - < 6.5 µmol/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: 95% CL
Duration:
15 min
Dose descriptor:
LOEC
Effect conc.:
ca. 0.15 µmol/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: 95% CL
Duration:
15 min
Dose descriptor:
NOEC
Effect conc.:
ca. 0.01 µmol/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: 95% CL

IC50: 4.2 µmol/L (2.8 - 6.5 µmol/L)

NOEC: 0.01 µmol/L

Description of key information

Based on test results from publication nr 7.

NOEC: 0.01 µmol/L

TNT is 227.13 g/mol which is the same as 227.13 µg/µmol

NOEC is equal: 0.01 *227.13 = 2.2713 µg/L = 0.0022713 mg/L

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
2.271 µg/L

Additional information