Registration Dossier

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The 32 day NOEC is 0.8 mg/L for Pimephales promelas

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.8 mg/L

Additional information

Russom and Broderius (1991) studied the toxicity of benzene in an early life stage test with Pimephales promelas. The exposure concentrations were measured at least twice a week during the exposure period. The most sensitive endpoint reported by the authors is a LOEC of 1.6 mg/L for wet weight and length. This value was the most conservative reliable chronic endpoint for freshwater fish identified in the EU RAR for benzene (2008). As the effect observed at this concentration was between 10 -20% a NOEC can be calculated by dividing the LOEC by two.

Although Black et al (1982) report a more sensitive EC10 this value was discounted in the EU RAR for benzene (2008) and so is discounted here also.