Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Ethyl chloroacetate is included in the list of harmonised classifications and labellings and it is classified as Hazardous for the Aquatic Environment, Acute Category 1.

Experimental results are available from studies conducted in fish. However, no analytical monitoring was conducted during the study. Therefore, there is no evidence that the concentration of the substance was maintained during the test. ECOSAR calculations were conducted for both methyl chloroacetate and ethyl chloroacetate.

The analogue methyl chloroacetate which shares the same functional group with ethyl chloroacetate, also has comparable values for the relevant molecular properties for the aquatic toxicity endpoint. These properties are:

- a low log Pow value which is 0.94 -1.12 for ethyl chloroacetate and 0.63 for methyl chloroacetate,

- a high water solubility which is 20 g/l at approximately 20 ºC for ethyl chloroacetate and 51.6 g/l for methyl chloroacetate and

- similar molecular weights which are 122.55 for ethyl chloroacetate and 108.52 for methyl chloroacetate.

The outcome of these calculations is that the LC50 for fish for both substances is below 1 mg/l. These results support the classification for ethyl chloroacetate as Hazardous for the Aquatic Environment, Acute Category 1.

Experimental results from a publication are available in Daphnia with the substance ethyl chloroacetate. The 48 h EC50 for Daphnia was concluded to be 1.6 mg/l.

Based on a QSAR prediction, the 48-h EC50 for Selenastrum capricornutum is 20.8 mg/l (Multicase model; Danish EPA database).

Experimental results are available from a study conducted in anaerobic bacteria from a domestic water treatment plant with the substance ethyl chloroacetate. However, no analytical monitoring was conducted during the study. A validation of the results is not possible, as neither validation criteria had been documented, nor the absolute values of the gas production activities had been recorded within all the laboratory manuscripts of the fermentation tube tests.