Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Data on the toxicity of 2,3,3,3-Tetrafluoropropene are available for all three trophic levels (fish,Daphnia, algae). The most sensitive organism in acute toxicity testing was Oryzias latipes. In the study on the acute toxicity of the substance to fish a LC50 (96 h) of 33 mg/L (measured) was determined. The available study on Daphnia magna determined an EC50 of 65 mg/L (measured) . The EC50 (72 h) detected in the acute toxicity study on algae (Pseudokirchneriella subcapitata) was > 2.5 mg/L based on algal growth rate.

The long-term toxicity of the substance to fish was determined in a juvenile growth test following OECD 215. Based on the growth rate a NOEC (28 d) of 2.7 mg/L (measured) was determined. In a study on the chronic toxicity of the substance to Daphnia magna a NOEC (21 d) of 15.2 mg/L (measured) based on the reproduction rate was determined.

In a activated sludge respiration inhibition test the substance proved to be slightly toxic to waste water (activated sludge) bacteria at a concentration prepared by sparing 2,3,3,3-Tetrafluoropropene at a rate of ca. 25 ml/min for approximately 2.5 hours during the 3 hour contact time (22% inhibition of respiration rate of the sludge).

However, due to the product characteristics, the atmosphere is the main target environmental compartment and the substance will readily evaporate from the water body. As such it is unlikely that the substance reach concentrations, at which any significant toxicological effects on aquatic organisms have to be expected.