Registration Dossier
Registration Dossier
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EC number: 203-473-3 | CAS number: 107-21-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Based on the available information from the read-across approach It can be concluded that the inhibition of the degradation activity is not anticipated when the substance is introduced in appropriately low concentrations.
Key value for chemical safety assessment
Additional information
Since no test data on the toxicity of monoethylene glycol to aquatic microorganisms are available, a read-across approach with the structurally similar substance CAS 111 -46 -6 (DEG) was performed.
The effect of DEG on the respiration activity of activated sludge for a wastewater treatment plant treating predominantly domestic sewage was investigated in two guideline studies.
In a study following ISO 8192, which is equivalent to OECD 209, a 30 -min EC20 > 1995 mg/L was determined (BASF AG, 1982).
This result is also supported with the test conducted according to OECD Guidance 209 by Klecka et al. (1985).The 3 -h EC50 was determined to be > 1000 mg/L (nominal).
Based on the available information from the read-across approach It can be concluded that the inhibition of the degradation activity is not anticipated when the substance is introduced in appropriately low concentrations.
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