Registration Dossier

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Toxicity to soil macroorganisms except arthropods:
Conclusion: Results from 14-day earthworm toxicity studies show that DTDP and DIDP, an analog to DTDP, do not cause toxicity at high soil concentrations as determined in natural and artificial soils. Results from a 56-day earthworm reproduction study show that DINP, an analog to DTDP, does not cause reproductive toxicity at high soil concentrations as determined in an artificial soil. Based on the data, DTDP is not expected to be chronically toxic to earthworms.

Key value for chemical safety assessment

Additional information

The results of short-term and long-term soil macro-organism toxicity studies are reported as EC50 and NOEC values. The NOEC values from these studies represent the highest concentrations tested and measured under the conditions of the studies.

I5 Summary

The toxicity of DTDP and DIDP, an analog to DTDP, as measured by mortality to the earthworm (Eisenia fetida) was evaluated in 14-day studies using natural and artificial soils. The toxicity of di-isononyl phthalate ester (DINP), an analog to DTDP, as measured by reproduction to the earthworm (Eisenia fetida) was evaluated in a 56 day study using an artificial soil. No significant mortality was observed in natural and artificial soils dosed with DIDP after 14 days at a nominal loading rate of 10,000 mg/kg soil (dw), which measured 7,664 mg/kg natural soil (dw) and 8,435 mg/kg artificial soil (dw) (concentrations are from analyses of soils at test initiation). DINP did not effect earthworm (Eisenia fetida) reproduction, based on a 56-day limit study in artificial soil at a high measured concentration of 982.4 mg/kg soil (dw). Because DINP, DIDP, and DTDP are structurally similar and exhibit the same biological activity, these data support the conclusion that DTDP would also not effect earthworm toxicity or reproduction.