Registration Dossier

Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Cross-reference
Reason / purpose:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Principles of method if other than guideline:
OECD guideline 105 was not appropriate and the cloud point technique was used to determine the solubility of the test substance in water. Solubility was defined as the weight of the test substance that resulted in a non-cloudy solution.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Purity: not reported as such

Results and discussion

Water solubility
Water solubility:
2.1 g/L
Temp.:
26 °C
pH:
>= 4 - <= 9
Details on results:
pH was not measured, but is expected to be in the environmentally relevant range of pH 4-9, as defined in OECD 111, since there are no functional groups present on the compounds in the mixture that would have a significant impact on the pH. Only the first vial yielded a clear solution on visual inspection, therefore according to this approach the solubility in water was determined to be 2.1 g/L at 26°C for the bulk test substance.

Applicant's summary and conclusion

Conclusions:
solubility in water = 2.1 g/L at 26°C
Executive summary:

To determine the solubility at 26°C aliquots of test substance (0.0210, 0.0397, and 0.0610 g) were weighed into three separate vials. A 10 mL aliquot of deionised water was added to each vial. These vials were placed on a shaker at 26°C for 16 hours. The samples were then visually analysed for signs of saturation (i.e., turbidity or increased viscosity). The solubility was determined to be the last sample concentration that did not show signs of saturation. Only the first vial yielded a clear solution on visual inspection, therefore according to this approach the solubility in water was determined to be 2.1 g/L at 26°C for the bulk test substance.