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EC number: 931-597-4
CAS number: -
See Figures 3, 6, and 9 in Appendix E of the Study Report.
of 3 indicator metals (Cr, Cd, Pb) in blood were analysed in 2 male and
2 female satellite animals on study days 1, 14 and 28. Samples were
taken from the same animals predose, 1h and 6h after dosing; on study
day 14 only predose. Blood Pb concentrations showed dose-dependent
increases and modest accumulation during the study so that the predose
values on day 28 were about 1, 1, 2.5 and 4.5 µg/l in males and 1, 2, 4
and 7.5 µg/l in females at dose-levels of 0, 500, 1000 and 2000
mg/kg/day, respectively. Cr concentrations showed at most only very
slight increases and virtually no accumulation. Cd concentrations were
not affected by the treatment.
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