Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-816-9 | CAS number: 74-86-2
Endpoint summary
Administrative data
Description of key information
Additional information
Measured data are not available for the terrestrial toxicity endpoints. In accordance with column 2 of REACH Annex IX and X, the terrestrial toxicity tests do not need to be conducted if direct and indirect exposure of the soil is unlikely to occur. Acetylene is a gas at standard temperature and pressure and is expected to partition primarily to air. An indicated Kow of 0.37 would also indicate low potential to bioaccumulate therefore terrestrial toxicity tests are not required.
In the absence of measured data the ECOSAR ECOWIN v1.00 model (Nabholz and Mayo-Bean 2009) has been used to calculate the toxicity of acetylene to earthworms. The ECOSAR model is a reliable and appropriate QSAR model to apply to acetylene as it is based on a related chemical dataset that calculates the toxicity of neutral organic hydrocarbons whose mode of action is non-polar narcosis. The endpoint calculated here is therefore a reasonable estimate of its baseline toxicity. The 1-day LC50 for earthworms is estimated to be 67 ppm.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
