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EC number: 204-126-9
CAS number: 116-14-3
Substance is a gas of low solubility and is expected to quickly
disappear from the aquatic phase. Therefore, any impact on the aquatic
environment is expected to be low. According to 9.1.3 Column 2 of REACH
Annex VIII aquatic toxicity studies need not be conducted if there are
mitigating factors indicating that aquatic toxicity it unlikely to occur.
tetrafluoroethylene is a gas and the consequent difficulty to test it
meaningfully in aquatic media, no experimental aquatic toxicity data are
available. Instead, QSAR methods have been used to estimate the acute
toxicity of the substance to the aquatic organisms.
of TFE to fish, daphnia and algae were estimated using the US EPA
program ECOSAR v1.00 (2009).
acute toxicity to aquatic organisms
The predicted toxic concentrations for fish and daphnia are considerably
greater than the solubility limit of TFE in water of 110 mg/l, which was
only achievable in equilibrium with a gas phase containing 1 atmosphere
of TFE. The predicted Algae EC50 is below the solubility limit; however,
experience with other fluorocarbons shows that for this endpoint ECOSAR
v1.00 predictions tend to be signifcantly lower than experimental
values, and so the predicted algae EC50 of 64 mg/l for TFE may well be
conservative. Given that there is no direct or indirect exposure of the
aquatic environment to TFE, and that it will disappear rapidly from
water, likely concentrations would be orders of magnitude below the
solubility limit. Therefore, it is concluded that TFE will not be toxic
in the aquatic environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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