Registration Dossier
Registration Dossier
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EC number: 231-838-7 | CAS number: 7758-29-4
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Studies tend to indicate that polyphosphates are not absorbed as such in the intestinal tract, but they can be hydrolysed in vivo by enzymes with the formation of monophosphates, mainly orthophosphate and possibly pyrophosphate, which are then absorbed (Gosselin et al., 1952; Ebel, 1958). This is further supported by the fact that systemic effects of polyphosphates are very similar to those of orthophosphates. It was estimated that approximately two-thirds of ingested phosphates is absorbed from the gastro-intestinal tract.
No data have been identified with regard to dermal absorption properties. It is generally considered that the percutaneous absorption of salts or ionic substances is limited
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