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EC number: 476-160-4
CAS number: 54807-34-0
An acute toxicity study was conducted with Daphnia magna on the chemical NaDMH. Analysis of the test preparations at 0 and 48 hours showed measured test concentrations to be near nominal and so the results are based on nominal test concentrations only.There was no immobilisation in 20 daphnids exposed to a test concentration of 100 mg/L for a period of 48 hours. It was considered unnecessary and unrealistic to test at concentrations in excess of 100 mg/L. The acute toxicity of the test material to the freshwater invertebrate Daphnia magna has been investigated and gave a 48 hour EC50 of greater than 100 mg/L. Correspondingly the No Observed Effect Concentration was 100 mg/L.An acute toxicity study conducted with Daphnia magna was also conducted on the analogue chemical DMH. DMH was tested at nominal concentrations of 3000, 5000, 7000, 10000, 15000 mg/L. In the highest test concentrations of 15000 mg/L and 10000 mg/L, 100% mortality occurred within 12 and 48 hours respectively. There were partial kills of 55% in the 7000 mg/L and 35% in the 5000 mg/L concentrations within 24 hours. No deaths were recorded in the 3000 mg/L or control test chambers. The LC50 was estimated to be 6200 mg/L as determined by the Litchfield & Wilcoxon Method.
As previously stated one of these studies
has been performed on DMH (Dimethyl Hydantoin) and has been used for
read-across purposes. A summary of data for read-across of NaDMH with
DMH is given in Section 13.
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