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Registration Dossier
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EC number: 932-349-8 | CAS number: 8006-64-2
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- Beta-Pinene is a main constituent of UVCB substance gum tupentine oil. Therefore, data on beta-pinene can be used for extrapolation to gum turpentine oil. See read-across justification document in section 13.
- Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- Not applicable
- Analytical method:
- gas chromatography
- Type:
- Pow
- Partition coefficient:
- 26 610
- Temp.:
- 25 °C
- Remarks on result:
- other: ± 340
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.425
- Temp.:
- 25 °C
- Remarks on result:
- other: ± 0.005
- Conclusions:
- The partition coefficient, Kow (mol/mol), of β-Pinene was measured to be 26610 ± 340, which corresponds to a log Kow of 4.425 ± 0.005 at 25°C.
- Executive summary:
A study was conducted to determine the partition coefficient of β-pinene using the shake-flask method (de Bruijn et al., 1989; Dewulf et al., 1999)and similarly to OECD Guideline 107. Octanol phase with test substance was thoroughly mixed with water to reach the partition equilibrium. After separation by centrifugation, concentration of the test substance in the octanol phase was determined by gas chromatography and the partition coefficient was calculated.
The partition coefficient, Kow (mol/mol), of β-pinene was measured to be 26610 ± 340, which corresponds to a log Kow of 4.425 ± 0.005 at 25 °C.
- Endpoint:
- partition coefficient
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- Alpha-Pinene is a main constituent of UVCB substance gum tupentine oil. Therefore, data on alpha-pinene can be used for extrapolation to gum turpentine oil. See read-across justification document in section 13.
- Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- Not applicable
- Analytical method:
- gas chromatography
- Type:
- Pow
- Partition coefficient:
- 30 670
- Temp.:
- 25 °C
- Remarks on result:
- other: ± 260
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.487
- Temp.:
- 25 °C
- Remarks on result:
- other: ± 0.004
- Conclusions:
- The partition coefficient, Kow (mol/mol), of α-pinene was measured to be 30670 ± 260, which corresponds to a log Kow of 4.487 ± 0.004 at 25°C.
- Executive summary:
A study was conducted to determine the partition coefficient of α-pinene using the shake-flask method (de Bruijn et al., 1989; Dewulf et al., 1999) and similarly to OECD Guideline 107. Octanol phase with test substance was thoroughly mixed with water to reach the partition equilibrium. After separation by centrifugation, concentration of the test substance in the octanol phase was determined by gas chromatography and the partition coefficient was calculated.
The partition coefficient, Kow (mol/mol), of α-pinene was measured to be 30670 ± 260, which corresponds to a log Kow of 4.487 ± 0.004 at 25°C.
Referenceopen allclose all
None
None
Description of key information
Measured log Kow of the two main constituents of gum turpentine oil (alpha-pinene and beta-pinene) were between 4.43 and 4.49.
The key value taken into account for gum turpentine oil is log Kow = 4.49.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.49
- at the temperature of:
- 25 °C
Additional information
The key value for alpha pinene is derived from a study using the shake-flask method and giving a log Kow = 4.49 at 25 °C.
The key value for beta-pinene is derived from a study using the shake-flask method with beta-pinene and giving a logPow= 4.42 at 25 °C.
These values are in the same magnitude of order, all slightly below 4.5.
Alpha pinene is the main constituent of gum turpentine oil (20-80%). Moreover, its log Kow based on a measured value from a relevant study (shake flask method at 25°C) can be considered as worst case for potential of bioaccumulation.
Therefore, the key value taken into account for gum turpentine oil is log Kow = 4.49.
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