Registration Dossier
Registration Dossier
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EC number: 200-755-8 | CAS number: 71-48-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008-09-15 to 2008-09-22
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- - Stability of the test substance is missing. - i) no method validation was performed (ii) no determination at 10 and 30 °C was performed, hence no conclusion possible if the water solubility of the substance is dependent on temperature (iii) no GLP certificate available Remark: Due to the fact that a further water solubility study (k_Walker_and_White_2008_water_solubility) was performed in a second laboratory with this test substance with analogue results the study could be regarded as valid.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- adopted 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- , 1992
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- 348 040 mg/L
- Temp.:
- 20 °C
- pH:
- ca. 6.29
- Details on results:
- During this study the water solubility at 20 °C was determined and found to be 348.04 g/L based on a measured concentration of 82.35 g Co/L (+/- 2.325 g Co/L) using the flask shaking method.
- Conclusions:
- Interpretation of results: very soluble (> 10000 mg/L)
During this study the water solubility at 20 °C was determined and found to be 348040 mg/L based on a measured concentration of 82.35 g Co/L (+/- 2.325 g Co/L) using the flask shaking method. - Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008-09-13 to 2008-10-01
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- 360 g/L
- Temp.:
- 20 °C
- pH:
- 5.6
- Details on results:
- Mean test material concentration: 360 g/L at 20.0 +/- 0.5°C
Range: 352 to 367g/L - Conclusions:
- Interpretation of results: very soluble (> 10000 mg/L)
The water solubility of the test material has been determined to be 360 g/L of solution, at 20.0 +/- 0.5°C.
Referenceopen allclose all
Description of key information
Cobalt diacetate has a water solubility of 348040 mg/L and of 360 g/L at 20 °C. The median of 354 g/L will be used for CSA.
Key value for chemical safety assessment
- Water solubility:
- 354 g/L
- at the temperature of:
- 20 °C
Additional information
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