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EC number: 204-694-8
CAS number: 124-28-7
Standard tests for bacterial sensitivity:
+ Increased reversion (his - to his +) over solvent controls
- No increase in reversion
The material was examined for mutagenic activity in two
histidine-dependent auxotrophs of Salmonella typhimurium, strains TA 98
and TA 100, using plate-incorporation assays.
The studies, which were conducted in the presence and absence of an
activiting system derived from rat liver (S-9 mix), employed a range of
levels of the substance from 5 to 500 µg per plate, selected following a
preliminary toxicity test in strain TA 98. The test included solvent
(ethanol) controls with and without S-9 mix.
The substance did not exhibit any mutagenic activity under the
conditions of test. Positive controls were effective, such indicating
the validity of the test system.
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