Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-694-8
CAS number: 124-28-7
Reliable screening studies on biodegradation are available for eight out of ten DMA category members. These altogether 15 studies (4x RL 1, 11x RL 2) were performed according to OECD 301 guidelines and consistently demonstrated ready biodegradability of DMA.
A pass-level criterion for most OECD 301-tests is the 10-day
window requirement. For some of the studies summarized below this was
not met. However, as all of the DMA category members consist of mixtures
of substances with varying hydrocarbon chain lengths, the 10-d window isgenerally
notapplicable for these substances.
Key studies for DMA category members C10, C12, C12-14, C14 and
C12-18 DMA were performed according to OECD 301B (CO2-Evolution).
Degradation levels between 67% (C12-14 DMA) and 93% (C12-18 DMA) were
achieved within 28 days and thus for all of them the pass level for
ready biodegradability is met. Several supporting studies performed
according to OECD 301-guidelines are available corroborating these
results (inherent biodegradability test for C14-DMA, ready
biodegradability test for the other four compounds).
Key studies for DMA category members C16, C16-18, and C18 DMA were
performed according to OECD 301D (Closed bottle test). Degradation
levels within 28 days were 60% for C16 DMA and 68% for C18 DMA, again
demonstrating ready biodegradability. In the closed bottle test with
C16-18 DMA 58% degradation were achieved within 28 days and 66% within
42 days. For this compound an additional reliable (with restrictions)
mechanistic (supporting) study is available, demonstrating ready
biodegradability using a variety of inocula, namely activated sludge,
river water, ditch water and soil. Furthermore, in this study
mechanistic aspects of degradation were elucidated using isolated
bacterial strains corroborating biodegradability for the category in
general. Supporting studies are also available for C16 and C18 showing
ready and inherent biodegradability, respectively.
In conclusion, from the broad experimental database it can be
concluded with that DMA category members are readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again