Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In accordance with Section 2 of REACH Annex XI, studies on skin sensitisation do not need to be conducted as members of the Petroleum Gases category are flammable gases at room temperature. No studies have been conducted on skin sensitisation and there are no indications from repeat dose studies or the published literature that any of the gases cause skin sensitisation.


Migrated from Short description of key information:
There are no data on skin sensitisation and no indications that members or main constituents of the Petroleum Gases are skin sensitisers. All are flammable gases at room temperature and therefore studies on skin sensitisation are waived.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

No respiratory sensitisation studies have been conducted on members of the Petroleum Gases category and there are no indications from other studies to suggest they cause respiratory sensitisation. Furthermore, there is a long history of the commercial use of Petroleum Gases and there are no reports from the available literature of respiratory sensitisation. 


Migrated from Short description of key information:
No studies have been conducted, but there no indications that members of Petroleum Gases are respiratory sensitisers.

Justification for classification or non-classification

There is no indication that members of the Petroleum Gases category cause skin or respiratory sensitisation and therefore, according to DSD and CLP criteria, no classification is warranted.