Registration Dossier
Registration Dossier
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EC number: 203-401-0 | CAS number: 106-47-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented publication which meets basic scientific principles
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Messung der Bioelimination von Chloranilinen
- Author:
- Janicke W, Hilge G
- Year:
- 1 980
- Bibliographic source:
- GWF-Wasser/Abwasser, 121:131¿135
- Reference Type:
- review article or handbook
- Title:
- p-Chloranilin
- Author:
- Gesellschaft Deutscher Chemiker (GDCh)
- Year:
- 1 993
- Bibliographic source:
- Beratergremium für umweltrelevante Altstoffe (BUA). Wissenschaftliche Verlagsgesellschaft, BUA-Stoffbericht 153
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- yes
- Remarks:
- ; methodology not described in detail.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-chloroaniline
- EC Number:
- 203-401-0
- EC Name:
- 4-chloroaniline
- Cas Number:
- 106-47-8
- Molecular formula:
- C6H6ClN
- IUPAC Name:
- 4-chloroaniline
- Details on test material:
- - Name of test material (as cited in study report): p-Chloranilin
- Analytical purity: not reported
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- no further data
- Duration of test (contact time):
- 30 d
Initial test substance concentration
- Initial conc.:
- 2 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 30 d
Any other information on results incl. tables
The closed bottle test (OECD 301D) showed no biodegradation
after 30 days .4 -chloroaniline - tested concentrations were in the range of measured
toxicity for bacteria.
Applicant's summary and conclusion
- Interpretation of results:
- under test conditions no biodegradation observed
- Executive summary:
No degradation of 4 -Chloroaniline was found in a standardized test similar to the OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test) (Janicke and Hilge, 1980).
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