Registration Dossier
Registration Dossier
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EC number: 240-085-3 | CAS number: 15956-58-8
Toxicity to other aquatic organisms
Administrative data
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Estimated by calculation
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of manganese and zinc to Boreal toad tadpoles (Bufo boreas)
- Author:
- Davis H, Brinkman S and McIntyre M
- Year:
- 1 998
- Bibliographic source:
- Federal aid project #F-243R-5, , Colorado Division of Wildlife, Fort Collins, Colorado
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Manganese sulphate
- EC Number:
- 232-089-9
- EC Name:
- Manganese sulphate
- Cas Number:
- 7785-87-7
- Molecular formula:
- H2O4S.Mn
- IUPAC Name:
- Manganese(II) sulphate
- Details on test material:
- - Name of test material (as cited in study report): Manganese sulphate monohydrate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test organisms
- Test organisms (species):
- Bufo boreas
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 10 d
Results and discussion
Effect concentrations
- Duration:
- 10 d
- Dose descriptor:
- EC50
- Effect conc.:
- 20.8 mg/L
- Conc. based on:
- other: Mn
- Basis for effect:
- mortality
Any other information on results incl. tables
Manganese concentrations were stable throughout the 24 hour period between renewals.
Mortality did not occur in manganese exposures of 10 mg Mn/L or less. In the 50 mg/L exposure, 40% mortality occurred by 96 hours leading to complete mortality by 168 hours. Mortality in the 100 mg/L exposure started as soon as 24 hours and resulted in complete mortality by 96 hours. The 96 and 168 hour LC50 were 42.3 and 20.8 mg Mn/L respectively
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The 96-h LC50 was 42.3 mg Mn/L
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