Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1998
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Method very poorly described

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1998
Report date:
1998

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
not specified
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(4-methyl-2-nitrophenylazo)-2-naphthol
EC Number:
219-372-2
EC Name:
1-(4-methyl-2-nitrophenylazo)-2-naphthol
Cas Number:
2425-85-6
Molecular formula:
C17H13N3O3
IUPAC Name:
1-[(E)-2-(4-methyl-2-nitrophenyl)diazen-1-yl]naphthalen-2-ol
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
Purity: 96.6%
Temperature: 25 +/- 2 °C

Test organisms

Test organisms (species):
Oryzias latipes

Study design

Total exposure duration:
48 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 400 mg/L
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
> 400 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The test substance has a low acute toxicity to fish (Oryzias latipes) with LC48h > 400 mg/L high above the water solubility of the test substance.