Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Mode of Action Analysis / Human Relevance Framework

Additional information

Justification for classification or non-classification

Available data at supplier from many repeated dose studies ranging from 28-day and OECD 422 screening studies, 90-day studies and incidental chronic and carcinogenicity studies, indicates that the toxicological profile of all the polyamines tested so far (including diamines, some salts and ethoxylated substances) all show the same profile.

As the non-acetate polyamine, Tallow dipropylene triamine (C12-18dipropylene triamine) is classified for STOT-RE Cat. 2 (with indicated organ gastro-intestinal system), it is prudent to classify(Z)-N-(3-aminopropyl)-N'-9 octadecenylpropane-1,3-diamine acetatesimilarly.