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EC number: 205-739-4
CAS number: 149-44-0
eye irritation/corrosion of the test item was tested in 3 Albino
Rabbits. The test item was instilled as the original substance after
crushing with a pestle and mortar to a fine dust at a single dose of 0.1
g to one of the eyes in each animal. The untreated eye was used for
were examined for clinical signs and the eyes were examined for lesions
of the conjunctivae, cornea and iris 1, 24, 48 and 72 h and on the 4th
day after instillation of the test item.
for ocular lesions were recorded in accordance with OECD 405.
instillation of the test item caused a slight redness of the
conjunctivae and a slight to short clear swelling of the conjunctivae in
3 three animals.
On the 4thday
after instillation no signs of irritations were observed. The cornea and
iris were not affected. None of the animals died or showed clinical
signs during the course of testing. Signs
of systemic effects of the test item were not observed.
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