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Physical & Chemical properties

Melting point / freezing point

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Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: original reference not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
no data
GLP compliance:
not specified
Melting / freezing pt.:
51.9 °C
Remarks on result:
other: The atmospheric pressure was not reported.
Executive summary:

Sax, 1968


The melting point of 4-nitrotoluene is 51.9 °C (the corresponding atmospheric pressure was not reported).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
no data
GLP compliance:
not specified
Melting / freezing pt.:
53 - 54 °C
Remarks on result:
other: The atmospheric pressure was not reported.
Executive summary:

NIOSH (National Institute for Occupational Safety and Health), 2009


The melting point of 4-nitrotoluene is reported to be in the range of 53-54 °C (the corresponding atmospheric pressure was not reported).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Melting / freezing pt.:
51 °C
Remarks on result:
other: The atmospheric pressure was not reported.
Executive summary:

Hommel, 1997


The melting point of 4-nitrotoluene is 51 °C (atmospheric pressure was not reported).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
no data
GLP compliance:
not specified
Melting / freezing pt.:
51.3 °C
Remarks on result:
other: The atmospheric pressure was not reported.
Executive summary:

MITI, 1992


The melting point of 4-nitrotoluene is 51.3 °C (atmospheric pressure was not reported).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed surce, valid collection of data
GLP compliance:
not specified
Melting / freezing pt.:
51.6 °C
Remarks on result:
other: The atmospheric pressure was not reported.
Executive summary:

Lide, D.R., 2001


The melting point of 4-nitrotoluene is 51.6 °C (atmospheric pressure was not reported).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Melting / freezing pt.:
55 °C
Remarks on result:
other: The atmospheric pressure was not reported.
Executive summary:

ROEMPP, 2009


The melting point of 4-nitrotoluene is 55°C (atmospheric pressure was not reported).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Melting / freezing pt.:
53.5 °C
Remarks on result:
other: The atmospheric pressure was not reported.
Executive summary:

Dugal, M. (Kirk-Othmer), 2005


The melting point of 4-nitrotoluene is reported as 53.5 °C (atmospheric pressure was not reported).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Adopted according to OECD SIDS (public available peer reviewed source)
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
published data; cited in OECD-SIDS
GLP compliance:
not specified
Melting / freezing pt.:
51.3 °C
Remarks on result:
other: The atmospheric pressure was not reported.
Executive summary:

OECD-SIDS, 2003:


The handbook data of Verschueren (Verschueren, K. (1996) Handbook of Environmental Data on Organic Chemicals; 3. ed.) was selected as the key value because the majority of the melting point values are in the range of 51 - 52 °C. Two print publications report 51.3 °C and some other sources very similar values. The latest value, the 2002 data (54 °C) differs from most other values.

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Specific details on test material used for the study:
- Name of test material (as cited in study report): 4-Nitrotoluene
- Analytical purity: not specified
Melting / freezing pt.:
44.5 °C
Remarks on result:
other: (unstable)
Melting / freezing pt.:
51.9 °C
Remarks on result:
other: (stable)

The atmospheric pressure was not reported.

Executive summary:

Booth, G. (Ullmann's), 2005


4-Nitrotoluene has a melting point of 51.9 °C (stable form). The atmospheric pressure was not reported.

Description of key information

The melting point of 4-nitrotoluene was determined in a series of experimental studies to be in the range of 51-55 °C.


The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.


Booth, G. (Ullmann's), 2005


4-Nitrotoluene has a melting point of 51.9 °C (stable form). The atmospheric pressure was not reported.


OECD-SIDS, 2003


The handbook data of Verschueren (Verschueren, K. (1996) Handbook of Environmental Data on Organic Chemicals; 3. ed.) was selected as the key value because the majority of the melting point values are in the range of 51 - 52 °C. Two print publications report 51.3 °C and some other sources very similar values. The latest value, the 2002 data (54 °C) differs from most other values.


Dugal, M. (Kirk-Othmer), 2005


The melting point of 4-nitrotoluene is reported as 53.5 °C (atmospheric pressure was not reported).


ROEMPP, 2009


The melting point of 4-nitrotoluene is 55°C (atmospheric pressure was not reported).


Lide, D.R., 2001


The melting point of 4-nitrotoluene is 51.6 °C (atmospheric pressure was not reported).


MITI, 1992


The melting point of 4-nitrotoluene is 51.3 °C (atmospheric pressure was not reported).


Hommel, 1997


The melting point of 4-nitrotoluene is 51 °C (atmospheric pressure was not reported).


NIOSH (National Institute for Occupational Safety and Health), 2009


The melting point of 4-nitrotoluene is reported to be in the range of 53-54 °C (the corresponding atmospheric pressure was not reported).


Sax, 1968


The melting point of 4-nitrotoluene is 51.9 °C (the corresponding atmospheric pressure was not reported).


 


The value reported in Ullmann's handbook (51.9 °C, stable form) was chosen as key value for chemical safety assessment, as stable and unstable form were distinguished.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
51.9 °C

Additional information