4-nitrotoluene

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising liquids

Type of information:

experimental study

Remarks:

expert statement based on an experimental study conducted with the closely related 3-Nitrotoluene (CAS 99-08-1)

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.21 (Oxidising Properties (Liquids))

Deviations:

no

GLP compliance:

not specified

Contact with:

other: cellulose

Sample tested:

test mixture as specified

Remarks:

mixtures of the sample with cellulose (ratio 1 : 1)

Parameter:

mean pressure rise time

Result:

6 850 ms

Remarks on result:

other: calculated from given data (see Table below), mean, n=5

Sample tested:

reference mixture as specified

Remarks:

Reference: 65 % Nitric acid + cellulose (1 : 1 ratio)

Parameter:

other: pressure rise time of reference mixture

Result:

2 550 ms

Remarks on result:

other: single value

3-nitrotoluene (CAS 99-08-1) was found "not to have oxidising properties" after the following results were obtained:

 

Test run	Sample amount	Maximum pressure	Time for pressure rise from 690 kPa to 2070 kPa	Remarks
1	2,5 g	2688 kPa	6875 ms	No spontaneous ignition
2	2,5 g	2750 kPa	5250 ms	No spontaneous ignition
3	2,5 g	2688 kPa	8125 ms	No spontaneous ignition
4	2,5 g	2844 kPa	7875 ms	No spontaneous ignition
5	2,5 g	2625 kPa	6125 ms	No spontaneous ignition
	2,5 g	2594 kPa	2550 ms	Reference: 65 % Nitric acid + cellulose (1 : 1 ratio)

 

Study report 2009/01372e and 2009/01684e:

4-nitrotoluene is expected to behave similarly. It is concluded that 4-nitrotoluene has no oxidsing properties either.

 

The decomposition behaviour determined by differential thermal analysis (DTA) was very similar for both compounds:

DTA measurement of 4-nitrotoluene (CAS 99-99-0), report 2009/01372e and 2009/01684e

Onset of exotherm: 286 °C 
Heat release: 1900 J/g

DTA measurement of 3-nitrotoluene (CAS 99-08-1), 2009/01371e

Onset of exotherm: 275 °C
Heat release: 1950 J/g

Interpretation of results:

GHS criteria not met

Remarks:

no oxidising properties

Executive summary:

Heitkamp D and Keldenich H-P (Currenta), 2009 [study report 2009/01371e]

A test conducted according to the Guideline EC A.21 showed that the mean pressure rise time for 3-nitrotoluene (6850 ms; five run tests) was longer than the pressure rise time for the reference substance (65% nitric acid, 2550 ms; single value). Furthermore, no spontaneous ignition was observed. Therefore, 3-nitrotoluene was found to have no oxidising properties.

 

Conclusion for 4-nitrotoluene based on the read across with 3-nitrotoluene

The structurally closely related 3-nitrotoluene did not show any oxidising properties in the EC A.21 test. 4-Nitrotoluene is expected to behave similarly, and no testing is required. It is concluded that 4-nitrotoluene has no oxidising properties either.

Description of key information

Heitkamp D and Keldenich H-P (Currenta), 2009 [study report 2009/01371e]

A test conducted according to the Guideline EC A.21 showed that the mean pressure rise time for 3-nitrotoluene (6850 ms; five run tests) was longer than the pressure rise time for the reference substance (65% nitric acid, 2550 ms; single value). Furthermore, no spontaneous ignition was observed. Therefore, 3-nitrotoluene was found to have no oxidising properties.

 

Conclusion for 4-nitrotoluene based on the read across with 3-nitrotoluene

The structurally closely related 3-nitrotoluene did not show any oxidising properties in the EC A.21 test. 4-Nitrotoluene is expected to behave similarly, and no testing is required. It is concluded that 4-nitrotoluene has no oxidising properties either.

Key value for chemical safety assessment

Oxidising properties:

non oxidising