Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
biochemical or cellular interactions
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: special in-vitro investigation; Documentation regarding DMBA is very limited

Data source

Reference
Reference Type:
publication
Title:
Cytoplasmic vacuolation of mouse peritoneal macrpohages and uptake into lysosomes of weakly basic substances|J.
Author:
Okuma S, Poole B
Year:
1981
Bibliographic source:
Cell Biology 90: 656-664

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzyldimethylamine
EC Number:
203-149-1
EC Name:
Benzyldimethylamine
Cas Number:
103-83-3
Molecular formula:
C9H13N
IUPAC Name:
benzyldimethylamine

Results and discussion

Any other information on results incl. tables

RS-Freetext:
Dimethyl-benzyl-amine causes large lysosomal vacuoles in mouse peritoneal macrophages in vitro.

Applicant's summary and conclusion