Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

Glucuronidation is one of the important pathways for the clearance of chemical compounds in mammals.

Kinetic parameters for the glucuronidation of 6 -tert-butyl-p-cresol and several other phenolderivatives was determined in vitro using pooled human and rat liver microsomes. Km and Vmax values were determined

Glucuronidation of 6 -tert-butyl-p-cresol is in rat liver microsomes greater than in human pooled liver microsomes