Registration Dossier

Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
other: reports of human sensitizations
Adequacy of study:
supporting study
Study period:
2005
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Review document of European Commission

Data source

Reference
Reference Type:
review article or handbook
Title:
Opinion on para-aminophenol
Author:
Scientific Committee on Consumer Products
Year:
2005
Report Date:
2005

Materials and methods

Study type:
other: case reports and epidemiological studies
Test guideline
Qualifier:
no guideline available
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Type of population:
other: human volunteers or occupationally exposed individuals
Ethical approval:
confirmed, but no further information available
Subjects:
Various; see results below
Route of administration:
dermal

Results and discussion

Applicant's summary and conclusion

Conclusions:
These studies when taken together with the animal studies would classify 4-aminophenol as a sensitizer.