1-Propanaminium, N-(carboxymethyl)-3-(formylamino)-N,N-dimethyl-, inner salt

GHS

General Information

Not classified

Implementation:

EU

Remarks:

Rationale for testing the substance as aqueous solution
The testing laboratory got the substance as an aqueous solution. The testing of the product in pure form is not practicable for the reasons set out below:
The product is obtained in the form of an aqueous solution containing active ingredient and sodium chloride. The manufacturing at higher contents of solids is not possible, because otherwise the solubility of the reactant sodium monochloroacetate is exceeded and no complete conversion to the registration substance is achieved.
The following attempts were made in the laboratory to isolate the substance from the aqueous solution:
To purify the product (partial desalination) the water was distilled in vacuum at elevated temperature. The substance was present as a highly viscous liquid, which solidified on cooling to a tough, glassy mass. Therefore, the product was dissolved in ethanol at elevated temperature. During cooling in refrigerator sodium chloride crystallized and could be separated by filtration. By this, sodium chloride content can be reduced to 9% of the solids content. The ethanol was distilled under vacuum at elevated temperature, and the product was left as highly viscous liquid.
The product in this form (91% active, 9% sodium chloride) solidified at room temperature to a tough, glass-like mass that could not be handled (poured, weighed, crushed, ...) or brought back into solution. An application or processing in this form is not possible. In addition, this substance is highly hygroscopic. For this reason, the hot substance was diluted with water thus converted into an easily manageable, liquid form. At higher solids content, the solution changes during time (formation of precipitates, turbidity) and by this a uniform composition over time cannot be guaranteed.
Conclusion
Thus the physical form oft the substance submitted for testing (aqueous solution) is the highest technically feasible active ingredient content concentration. It contains additional substances as water and sodium chloride. The concentration oft commercially marketed products, now and in future, for the reasons given above, doesn’t exceed this concentration.

Related composition

Related composition:

480-680-7

Classification

Physical hazards

Explosives

Reason for no classification:

data conclusive but not sufficient for classification

Flammable gases and chemically unstable gases

Reason for no classification:

data conclusive but not sufficient for classification

Aerosols

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

hazard class not assessed

Oxidising gases

Reason for no classification:

data conclusive but not sufficient for classification

Gases under pressure

Reason for no classification:

data conclusive but not sufficient for classification

Flammable liquids

Reason for no classification:

data conclusive but not sufficient for classification

Flammable solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-reactive substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric liquids

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-heating substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Substances and mixtures which in contact with water emit flammable gases

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising liquids

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising solids

Reason for no classification:

data conclusive but not sufficient for classification

Organic peroxides

Reason for no classification:

data conclusive but not sufficient for classification

Corrosive to metals

Reason for no classification:

data lacking

Desensitized explosives

Reason for no classification:

data lacking

Health hazards

Acute toxicity - oral

Reason for no classification:

data conclusive but not sufficient for classification

Acute toxicity - dermal

Reason for no classification:

data conclusive but not sufficient for classification

Acute toxicity - inhalation

Reason for no classification:

data lacking

Skin corrosion / irritation

Reason for no classification:

data conclusive but not sufficient for classification

Serious eye damage / eye irritation

Reason for no classification:

data conclusive but not sufficient for classification

Respiratory sensitisation

Reason for no classification:

data lacking

Skin sensitisation

Reason for no classification:

data conclusive but not sufficient for classification

Aspiration hazard

Reason for no classification:

data lacking

Reproductive toxicity

Reason for no classification:

data conclusive but not sufficient for classification

Effects on or via lactation

Reason for no classification:

data lacking

Germ cell mutagenicity

Reason for no classification:

data conclusive but not sufficient for classification

Carcinogenicity

Reason for no classification:

data lacking

1. Specific target organ toxicity - single (STOT-SE)

Reason for no classification:

data conclusive but not sufficient for classification

1. Specific target organ toxicity - repeated (STOT-RE)

Reason for no classification:

data conclusive but not sufficient for classification

Environmental hazards

Hazardous to the aquatic environment (acute / short-term)

Reason for no classification:

data conclusive but not sufficient for classification

Hazardous to the aquatic environment (long-term)

Reason for no classification:

data lacking

Hazardous to the ozone layer

Reason for no classification:

data lacking

Labelling

Signal word:

No signal word