2-nitrotoluene

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

other information

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Specific details on test material used for the study:

- Analytical purity: not specified

Temp.:

25 °C

Vapour pressure:

0.188 mm Hg

Remarks on result:

other: extrapolated

Executive summary:

HSDB, 2009

The vapour pressure of 2-nitrotoluene is reported as 0.188 mm Hg (corresponds to 0.25 hPa) at 25 °C

Reference 2

Endpoint:

vapour pressure

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Accepted calculation method

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

vapour pressure equation

GLP compliance:

not specified

Temp.:

25 °C

Vapour pressure:

0.25 hPa

Remarks on result:

other: read from the equation

Temp.:

20 °C

Vapour pressure:

0.17 hPa

Remarks on result:

other: read from the equation

Temp.:

50 °C

Vapour pressure:

1.3 hPa

Remarks on result:

other: read from the equation

Temp.:

55 °C

Vapour pressure:

1.8 hPa

Remarks on result:

other: read from the equation

Coefficients for vapour pressure equation

log₁₀ P = A + B/T + C log₁₀ T + D T + E T² with P in mm Hg and T in K

are given for 2-nitrotoluene:

 

A = 7.8266

B = -2.9908E+03

C = 1.1064E+00

D= -4.9168E-03

E = 2.2375E-06

 

temperature range: 270 K - 720 K

Executive summary:

Handbook of Vapor Pressure (Yaws, 1994)

The coefficients for the vapour pressure equation

log10 P = A + B/T + C log10 T + D T + E T2 with P in mm Hg and T in K

are given for 2-nitrotoluene as:

A = 7.8266

B = -2.9908E+03

C = 1.1064E+00

D= -4.9168E-03

E = 2.2375E-06

for the temperature range: 270 K - 720 K

By the use of this equation the vapour pressure of 2-nitrotoluene was calculated as 0.25 hPa at 25 °C and as 0.17 hPa at 20 °C.

Reference 3

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Specific details on test material used for the study:

- Name of test material (as cited in study report): 2-Nitrotoluol
- Analytical purity: not specified

Temp.:

20 °C

Vapour pressure:

0.16 hPa

Executive summary:

Roempp Online, 2009

The vapour pressure of 2-nitrotoluene is reported as 0.16 hPa at 20 °C.

Description of key information

The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.

The vapour pressure of 2-nitrotoluene was determined in a series of experimental studies and was calculated from the vapour pressure equation. The values are in a similar range.

Roempp Online, 2009

The vapour pressure of 2-nitrotoluene is reported as 0.16 hPa at 20 °C.

Handbook of Vapor Pressure (Yaws, 1994)

The coefficients for the vapour pressure equation

log10 P = A + B/T + C log10 T + D T + E T2 with P in mm Hg and T in K

are given for 2-nitrotoluene as:

A = 7.8266

B = -2.9908E+03

C = 1.1064E+00

D= -4.9168E-03

E = 2.2375E-06

for the temperature range: 270 K - 720 K

By the use of this equation the vapour pressure of 2-nitrotoluene was calculated as 0.25 hPa at 25 °C and as 0.17 hPa at 20 °C.

HSDB, 2009

The vapour pressure of 2-nitrotoluene is reported as 0.188 mm Hg (corresponds to 0.25 hPa) at 25 °C

Key value for chemical safety assessment

Vapour pressure:

0.25 hPa

at the temperature of:

25 °C