Registration Dossier
Registration Dossier
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EC number: 201-853-3 | CAS number: 88-72-2
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Executive summary:
Kirk-Othmer, 2005 (Dugal, M., 2005)
2-Nitrotoluene was found to be infinitely soluble in benzene, diethyl ether and ethanol as well as soluble in most organic solvents.
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Executive summary:
Merck Index, 2006
2-Nitrotoluene was found to be soluble in the following organic solvents: alcohol, benzene and petroleum ether.
Referenceopen allclose all
- infinitely soluble in benzene, diethyl ether and ethanol - soluble in most organic solvents
soluble in alcohol, benzene, petroleum ether
Description of key information
Merck Index, 2006
2-Nitrotoluene was found to be soluble in the following organic solvents: alcohol, benzene and petroleum ether.
Kirk-Othmer, 2005 (Dugal, M., 2005)
2-Nitrotoluene was found to be infinitely soluble in benzene, diethyl ether and ethanol as well as soluble in most organic solvents.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
