Registration Dossier
Registration Dossier
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EC number: 220-562-2 | CAS number: 2814-77-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1962
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Purity unknown and method is only partially described.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 962
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- no
Test material
- Reference substance name:
- 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol
- EC Number:
- 220-562-2
- EC Name:
- 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol
- Cas Number:
- 2814-77-9
- Molecular formula:
- C16H10ClN3O3
- IUPAC Name:
- 1-[(2-chloro-4-nitrophenyl)diazenyl]-2-naphthol
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- oral: gavage
- No. of animals per sex per dose:
- 10
Results and discussion
Effect levels
- Key result
- Dose descriptor:
- LD50
- Effect level:
- > 10 000 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- LD50 > 10,000 mg/kg bw
- Executive summary:
Three out of ten mouse died from an acute exposure to 10 g/kg bw of C.I. Pigment Red 4.
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