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EC number: 273-227-8
CAS number: 68953-84-4
toxicity to fish was determined in several species. Rainbow
trout (Oncorhynchus mykiss) (Dionne, 1997) appeared to be the
most sensitive fish species with regard to DAPD toxicity (in comparison
to a.o. common carp (Cyprinus carpio) (Dionne, 1995)). The
96h-LC50 value for Rainbow trout was 0.48, while the NOECs (96h) was
0.14 mg/L. After long-term, 14 -days exposure, lowest toxicity values
were still observed in Rainbow trout displayed by an EC50
of 0.26 mg/L and a NOEC of 0.14 mg/L after 14 days of exposure.
short-term toxicity test performed with Daphnia magna provided an
unbound EC50 value (immobility, 48h) > 1.8 mg/L, however a short-term
NOEC of 0.36 mg/L was established (Putt, 1995). The long-term
toxicity towards Daphnia magna was evaluated as well (Sacker,
2010). This resulted in an EC10(21 days; reproduction) of
0.0045 mg/L (estimated by extrapolation) and a Lowest Observed Effect
Concentration (LOEC - reproduction) of 0.007 mg/L. An actual NOEC for
reproductive effects could not be established. In the same test, the no
observed effect value (NOEC) for parent Daphnia survival (21
days) was 0.016 mg/L, the EC10(survival, 21 days) was 0.027
Toxicity towards freshwater algae:
the growth rate, the EC50 (72h) was determined to be above
0.079 mg/L while the NOEC (72h) was determined at 0.013 mg/L test
substance (Hoberg, 1996).
No substantial toxicity towards
microorganims was observed. The 3h-EC50 towards
microorganisms is > 20 mg/L (Drake, 2011).
To conclude, based on the acute toxicity
results presented here algae appear to be the most sensitive species.
The long-term toxicity results however indicate that the invertebrates
are more sensitive towards the chemical in comparison to the algae.
Therefore, the results obtained with the Daphnia are used for further
risk assessment purposes and key value in determining the PNECs.
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