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Environmental fate & pathways

Hydrolysis

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Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP, non-guideline study. Available as a published report. Limitations on reporting. Acceptable with restrictions.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1980

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Procedure as described in Wolfe et al. (1976) Agric. Food Chem., 24, 1041 and Wolfe et al (1977) Environ. Sci & Tech., 11, 88
Sodium hydroxide induced hydrolysis is monitored by GLC on samples.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Radiolabelling:
no

Study design

Analytical monitoring:
yes
Buffers:
LC- 0.3 M KH2PO4
Details on test conditions:
Tests were carried out at 30.00 +/- 0.05 ⁰C, never exceeding 10-5M and always below the water solubility of the ester.
Duration of test
Temp.:
30
Number of replicates:
Not reported
Positive controls:
not specified
Negative controls:
not specified
Statistical methods:
None

Results and discussion

Dissipation DT50 of parent compound
Temp.:
30 °C
Hydrolysis rate constant:
0.001
St. dev.:
0
Type:
second order
Remarks on result:
other: Units: M-1.s-1
Details on results:
Second order hydrolysis rate constant = (1.4 ± 0.2) * 10-3 M-1.s-1

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The second order hydrolysis rate constant of diisobutyl phthalte was found to be 0.0014 ± 0.0002 M-1.s-1
Executive summary:

In a non-GLP, non-guideline study the second order hydrolysis rate constant of diisobutyl phthalte was found to be 0.0014 ± 0.0002 M-1.s-1