Registration Dossier
Registration Dossier
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EC number: 204-557-2 | CAS number: 122-60-1
Endpoint summary
Administrative data
Description of key information
Although no data are available to the registrant for phenylglycidyl ether for skin irritation, in accordance with the harmonised scheme for classification and labelling in Regulation EC 1272/2008, phenylglycidyl ether (index number 603 -067 -00 -X) is a category 2 skin irritant and may cause respiratory irritation.
A single exposure inhalation study that was the preliminary test for the repeated dose inhalation study (Section 7.5.3) indicates that this substance may cause respiratory sensitisation, and in accordance with the harmonised scheme for classification and labelling in Regulation EC 1272/2008, phenylglycidyl ether (index number 603 -067 -00 -X) is a specific target organ toxicity (single exposure) category 3 (H335: May cause respiratory irritation).
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Effects on respiratory irritation: irritating
Effect level: empty Endpoint conclusion: Adverse effect observed
Justification for classification or non-classification
Classifications for irritation/corrosion of phenylglycidyl ether were made in accordance with the harmonised scheme for classification and labelling in Regulation EC 1272/2008 (index number 603 -067 -00 -X).
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