Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-772-0
CAS number: 72-17-3
RS-Freetext:No significant gross observations, with the exception ofminimal skin irritation. Absolute brain weight andkidney-to-body weight ratios were increased for testanimals.No lesions were observed at necropsy or at microscopicexamination.
All animals survived to study termination. No significant gross
observations, with the exception of minimal skin irritation throughout
the study, could be attributed to dosing. During week 7, the blood urea
nitrogen value was significantly increased for test ammals as compared
to controls; no other hematological effects were seen, and urinary
parameters were normal. Absolute brain weight and kidney-to-body weight
ratios were statistically significantly increased for the test animals.
No lesions were observed at necropsy or at microscopic exammation. The
investigators concluded this formulation is "safe in terms of cumulative
toxicity" and that "based upon the exaggerated dose level used in this
study for skin care products, dermal application is not likely to
produce adverse effects under conditions of consumer use."
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again