Registration Dossier
Registration Dossier
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EC number: 202-453-1 | CAS number: 95-80-7
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Carried out according to OECD Guideline with no analytical monitoring.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 982
- Report date:
- 1982
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 202 Part 2
- Deviations:
- yes
- Principles of method if other than guideline:
- 14 days NOEC (reproduction)
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-methyl-m-phenylenediamine
- EC Number:
- 202-453-1
- EC Name:
- 4-methyl-m-phenylenediamine
- Cas Number:
- 95-80-7
- Molecular formula:
- C7H10N2
- IUPAC Name:
- 4-methylbenzene-1,3-diamine
- Details on test material:
- 2,4-toluenediamine
'extra pure' 2,4-TDA (Tokyo Kasei)
Constituent 1
Test solutions
- Details on test solutions:
- Dilution water:
NaHCO3; 192 ppm,
CaSO4.2H2O; 120ppm,
MgSO4; 120ppm,
KCl; 8.0ppm.
Test organisms
- Test organisms (species):
- other aquatic crustacea: moina macrocopa
- Details on test organisms:
- Age: less than 24 hours old.
Feeding: once daily with unicellular green algae
40 organisms divided into four batches of ten
Newborn young of the F1 generation counted every 2 days.
Study design
- Test type:
- semi-static
- Total exposure duration:
- 14 d
Test conditions
- Test temperature:
- 20°C
- pH:
- 8
- Nominal and measured concentrations:
- Test substance concentrations: 0, 0.8, 1.6, 3.2, 6.3, 12.5 ppm
Results and discussion
Effect concentrations
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.8 other: ppm
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
