Registration Dossier

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1964
Report Date:
1964

Materials and methods

Type of study / information:
Phototoxicity
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Each agent was applied to the backs of ten (10) men under occlusion for twenty-four (24) hours. A control site was treated with petrolatum. Then, one minimal erythema dose was given to the treated and control sites using the erythema producing radiation produced by the Westinghouse FS-20 lamp. Photo-toxicity is indicated by a marked flare at the sites treated by the test agents.
GLP compliance:
no
Remarks:
Study pre-dates GLP

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Specific details on test material used for the study:
- Name of test material (as cited in study report): Tinuvin P

Results and discussion

Any other information on results incl. tables

A table of results is provided in the study report; however, the results were not fully described. It was concluded in the study report that CAS 2440 -22 -4 was not phototoxic.

Applicant's summary and conclusion