Registration Dossier
Registration Dossier
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EC number: 201-956-3 | CAS number: 89-98-5
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 1977
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Non-guideline study, insufficient documentation, only report of results without documentation of details
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 977
Materials and methods
- Principles of method if other than guideline:
- Acute dermal toxicity
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- 2-chlorobenzaldehyde
- EC Number:
- 201-956-3
- EC Name:
- 2-chlorobenzaldehyde
- Cas Number:
- 89-98-5
- Molecular formula:
- C7H5ClO
- IUPAC Name:
- 2-chlorobenzaldehyde
- Details on test material:
- - Name of test material (as cited in study report): o-chlorobenzaldehyde (E-757)
Constituent 1
Test animals
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- other: impervious cuff
- Vehicle:
- not specified
- Duration of exposure:
- no data
- Doses:
- 5.0 to 20.0 g/kg
- No. of animals per sex per dose:
- 3 animals at all
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- approximate LD50
- Effect level:
- 20 000 mg/kg bw
Applicant's summary and conclusion
- Executive summary:
In a study with guinea pigs which were dermally exposed to 5.0 to 20.0 g 2-chlorobenzaldehyde/kg bw no deaths were recorded.
Due to insufficient reporting the study was judged not to be reliable (RL3).
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