Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-547-2 | CAS number: 96-96-8
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- M143
- Author:
- RSC Publishing
- Year:
- 2 011
- Bibliographic source:
- Dictionary of Substances and their effects (DOSE):- Lenga, R. E. (Ed.) Sigma-Aldrich Library of Chemical Safety Data 2nd ed., 1988, 2, 2259, Sigma-Aldrich, Milwaukee, WI, USA.
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- DOSE database
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-nitro-p-anisidine
- EC Number:
- 202-547-2
- EC Name:
- 2-nitro-p-anisidine
- Cas Number:
- 96-96-8
- Molecular formula:
- C7H8N2O3
- IUPAC Name:
- 4-methoxy-2-nitroaniline
Constituent 1
Test animals
- Species:
- other: not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- unchanged (no vehicle)
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- animal: species unspecified
- Reversibility:
- no data
- Remarks on result:
- other: Irritating to the skin
- Irritant / corrosive response data:
- Irritating to the skin (species unspecified)
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Executive summary:
The substance is found to be irritating to the skin (species unspecified)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
