Registration Dossier
Registration Dossier
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EC number: 212-836-5 | CAS number: 873-32-5
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction
Data source
Reference
- Reference Type:
- publication
- Title:
- BUA-Stoffbericht 265 - 2-Chlorbezonitril, 4-Chlorbenzonitril
- Author:
- n.a.
- Year:
- 2 006
- Bibliographic source:
- Beratergremium für Altstoffe (BUA) der Gesellschaft Deutscher Chemiker, S.Hirzel Wissenschaftliche Verlagsgesellschaft
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- QSAR; calculation on basis of log Kow using EPISUITE 3.12 (US-EPA 2004)
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-chlorobenzonitrile
- EC Number:
- 212-836-5
- EC Name:
- 2-chlorobenzonitrile
- Cas Number:
- 873-32-5
- Molecular formula:
- C7H4ClN
- IUPAC Name:
- 2-chlorobenzonitrile
- Reference substance name:
- unknown
- IUPAC Name:
- unknown
- Test material form:
- solid
Constituent 1
impurity 1
Test organisms
- Test organisms (species):
- Daphnia sp.
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 72 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The calculated 48-h EC50 of 2-chlorobenzonitrile for Daphnia using EPISUITE 3.12 (US-EPA 2004) is 72 mg/L.
- Executive summary:
As no experimental data are available the 48-h EC50 of 2-chlorobenzonitrile for Daphnia was calculated using EPISUITE 3.12 (US-EPA 2004). The calculated 48-h EC50 is 72 mg/L.
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