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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Does not meet important criteria of today standard methods. Only a 50% dilution of the test substance was tested. No data on analytical purity of the test substance provided.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1981
Report date:
1981

Materials and methods

Principles of method if other than guideline:
Screening for dermal irritation in rabbits (Patch-Test)
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
1,2-Benzenedicarboxylic acid, mixed cetyl and stearyl esters
EC Number:
270-487-4
EC Name:
1,2-Benzenedicarboxylic acid, mixed cetyl and stearyl esters
Cas Number:
68442-70-6
Details on test material:
- Name of test material (as cited in study report): Ditalgfettalkoholphthalat (dihydrogenated tallow phthalate)
- Analytical purity: no data

Test animals

Species:
rabbit
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
other: untreated site of the same animal served as control
Amount / concentration applied:
TEST MATERIAL
- Amount(s) applied (volume or weight with unit): no data
- Concentration (if solution): 50 %
Duration of treatment / exposure:
4 hours
Observation period:
no data
Number of animals:
no data

Results and discussion

Any other information on results incl. tables

No dermal irritation observed. No further details on results given.

Applicant's summary and conclusion

Interpretation of results:
other: inconclusive
Remarks:
Criteria used for interpretation of results: EU