Registration Dossier

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only short description

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Shell Chemical Company. Unpublished report. 2401 Cro Canyon Rd., San Romon, CA 94583
Year:
1961
Bibliographic source:
cited in RTECS, EM4725000, 2006

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No data

Test animals

Species:
rabbit
Strain:
not specified
Details on test animals and environmental conditions:
No data

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
500 mg
Duration of treatment / exposure:
No data
Observation period:
No data
Number of animals:
No data
Details on study design:
No data

Results and discussion

In vivo

Results
Irritation parameter:
other: irritation
Basis:
other: no data
Time point:
other: no data
Score:
> 2
Reversibility:
not reversible
Remarks on result:
other: The data indicate that the test substance is corrosive (causes severe damage) to the skin although no scores are available.
Irritant / corrosive response data:
severe skin damage
Other effects:
No data

Any other information on results incl. tables

Results for the study are only available in descriptive form.

Applicant's summary and conclusion