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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
insufficient hazard data available (further information necessary)

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

According to Article 13 of Regulation (EC) No 1907/2006 "General Requirements for Generation of Information on Intrinsic Properties of substances", Information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met. Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X” states that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or ‘category’ of substances. This avoids the need to test every substance for every endpoint”. Since read-across was applied for the substance, data will be generated from representative source substances to avoid unnecessary animal testing. Additionally, once the read-across approach is applied, substances will be classified and labelled on this basis.

Degradation

Biodegradation: readily biodegradable: 76.3 - 79.9% after 28 d (OECD 301B, CO2 evolution), 86% after 28 d (OECD 301F, O2 consumption), read across

Bioaccumulation

Weight of evidence: Bioaccumulation is assumed to be low.

Aquatic acute toxicity

Fish
96 h, LC50 (Brachydanio rerio): > 10000 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

96 h, LC50 (Salmo trutta): > 1000 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

96 h, LL50 (Leuciscus idus melanotus): > 10000 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

96 h, LL50 (Scophthalmus maximus): > 3200 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

96 h, LC50 (Cyprinus carpio): > 100mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

 

Aquatic invertebrates
48 h, EL50 (Daphnia magna): > 100 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

48 h, EL50 (Daphnia magna): > 1000 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

48 h, EL50 (Daphnia magna): > 100 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

 

Aquatic algae
72 h, ErL50 (Desmodesmus subspicatus): > 100 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

72 h, ErL50 (Pseudokirchneriella subcapitata): > 1000 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

72 h, ErL50 (Scenedesmus subspicatus): > 100 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

 

Aquatic chronic toxicity

72 h, NOELR given as EL0 (Desmodesmus subspicatus): ≥ 100 mg/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

21 d, NOELR (Daphnia magna): ≥ 0.11 g/L (nominal; no observed toxicological effects up to the water solubility limit); read-across

CLP

Based on the data above,2-ethyl-2-(hydroxymethyl)-1,3-propanediyl dioleate (CAS 25111-05-1)is considered to be rapidly degradable. No acute aquatic toxicity was observed up to the water solubility limit (1.26 µg/L - 13.54 µg/L at 20 °C, pH=6.3 (OECD 105), mean: 7.40 µg/L) for fish, algae and daphnids. Valid chronic data are available with a NOELR (72 h) ≥ 100 mg/L for the algae Desmodesmus subspicatus and a NOELR (21 d) ≥ 0.11 g/L for Daphnia magna. Therefore,2-ethyl-2-(hydroxymethyl)-1,3-propanediyl dioleatedoes not need to be classified and labelled as environmental hazard according to the 2nd ATP of the Regulation (EC) No 1272/2008 (CLP).

DSD

The substance is poorly soluble in water and no effects occurred up to its solubility limit in acute tests for fish, algae and aquatic invertebrates. Therefore, 2-ethyl-2-(hydroxymethyl)-1,3-propanediyl dioleate (CAS 25111-05-1) does not need to be classified and labelled as environmental hazardous according to Directive 67/548/EEC.