Registration Dossier
Registration Dossier
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EC number: 200-306-6 | CAS number: 57-00-1
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no data available: testing technically not feasible
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
As a result of the environmental hazard assessment it can be concluded that creatine:
- Does not meet the criteria for classification as dangerous;
- Does not display effects lower than the criteria for classification and so the substance is not classified;
- Does not show hazards for which currently no classification criteria exist;
- Cannot be considered as PBT/vPvB.
Conclusion on classification
In all available tests on aquatic organisms neither lethal nor sublethal effects could be observed at creatine concentrations as high as 84.6 mg/L (mean measured concentration fish study), 880 mg/L (daphnia), and 100 mg/L (algae). Therefore, no E/LC50 values could be derived for the substance. In addition, creatine is readily biodegradable (71.2 % biodegradation within 10 days) and has a negligible potential for bioaccumulation (based on the measured log Kow of < -2).Thus, a classification for the environment is not warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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