Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
other information
Study period:
2001-04-10 to 2001-04-11
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002
Report Date:
2002

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
yes
Remarks:
Comment: Since the vapor pressure was expected to be very low, a mixture of substances was examined. If the vapor pressure of the mixture did not exceed a certain value, this would also be valid for every single substance.
GLP compliance:
yes
Type of method:
effusion method: vapour pressure balance

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Vapour pressure
Temp.:
25 °C
Vapour pressure:
< 0.001 Pa

Applicant's summary and conclusion

Executive summary:

The vapor pressure of ZK 34517 was determined using a screening method based on the

detection of the evaporation rate from a Knudsen cell of a vapor pressure balance at 25 °C.

Since simplified experimental conditions are also acceptable within the scope of this project, ZK

34517 was mixed with four other compounds. From all five test substances low or very low

vapor pressures, based on the study director´s experience, were expected. For this reason the

experiments consisted in the measurement of the evaporation rate of the mixture from a

Knudsen cell a 25 °C. Since the evaporation rate of the mixture was below the value derived

from the lower limit of the vapor pressure range recommended for the use of a vapor pressure

balance (1E-03 Pa, EC Testing Guideline A.4) it can be assumed that the vapor pressure of the

mixture is lower than 1E-03 Pa.

Considering this fact, the vapor pressure of the single compounds in the mixture has also to be

lower than 1E-03 Pa. Therefore, the vapor pressure of ZK 34517 can be estimated to be at 25 °C:

p25 < 1E-03 Pa.