Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Simple rules defining the potential of compounds for transdermal delivery or toxicity.
Author:
Magnusson et al.
Year:
2004
Bibliographic source:
Pharm Res 21(6):1047-54.
Reference Type:
publication
Title:
Molecular size as the main determinant of solute maximum flux across skin.
Author:
Magnusson et al.
Year:
2004
Bibliographic source:
J of Investigative Dermatology 122:993-999
Reference Type:
publication
Title:
Skin sensitisation and epidermal disposition: the relevance of epidermal disposition for sensitisation hazard identification and risk assessment.
Author:
BAsketter et al.
Year:
2007
Bibliographic source:
ATLA 35:137-154

Materials and methods

Results and discussion

Applicant's summary and conclusion