Registration Dossier
Registration Dossier
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EC number: 242-901-3 | CAS number: 19234-20-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72 h): > 100 mg/L for Pseudokirchneriella subcapitata (OECD 201)
NOEC (72 h): ≥ 100 mg/L for Pseudokirchneriella subcapitata (OECD 201)
Key value for chemical safety assessment
Additional information
One experimental study investigating the effects of 2-(1-methylethoxy)ethyl acetate (CAS 19234-20-9) to aquatic algae is available (Vryenhoef, 2012). The study was performed according to OECD 201 under GLP conditions with the freshwater algae Pseudokirchneriella subcapitata. A preliminary range-finding study with four concentrations up to 100 mg/L did not result in inhibition of growth. Therefore, a confirmatory limit test with 100 mg/L was performed. No inhibition of growth was observed in the definitive test either. Thus, an EC50 (72 h) > 100 mg/L (nominal) and a NOEC (72 h) ≥ 100 mg/L (nominal) were derived (based on both growth rate and yield). Measured concentrations were within the range of 80 - 120%. Therefore, the EC50 and the NOEC were based on the nominal concentrations only.
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