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EC number: 254-179-7
CAS number: 38888-98-1
SAS-40 was tested in the Salmonella typhimurium reverse mutation assay
according to OECD/EC guidelines with five histidine-requiring strains of
Salmonella typhimurium (TA1535, TA1537, TA1538, TA98 and TA100) with and
without metabolic activation (S9 -mix). The test was performed in two
independent experiments. The test substance did not induce a significant
dose-related increase in the number of revertant (His+) kolonies in any
of the strains. Both the solvent control and positive controls gave
results within expected ranges. Cytotoxicity was observed at ≥
1250 µg/ plate. Based on the results of this study it can be
concluded that SAS-40 is not mutagenic in the Salmonella typhimurium
reverse mutation assay.
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